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Infliximab Infusion for Crohn's Disease at Addenbrooke's NHS Hospital
Introduction to Infliximab (Remicade)
Infliximab, marketed under the brand name Remicade, is a biologic therapy used to treat autoimmune diseases like Crohn's Disease. It is administered through an intravenous infusion and works by targeting and inhibiting a substance in the body called tumor necrosis factor-alpha (TNFα), which plays a crucial role in inflammatory processes. At Addenbrooke's NHS Hospital, patients with Crohn's Disease can receive this treatment to help manage their symptoms and improve their quality of life.
Treatment Process at Addenbrooke's NHS Hospital
At Addenbrooke's NHS Hospital, the administration of infliximab is conducted under the supervision of experienced healthcare professionals. The infusion typically takes about 2-3 hours, during which patients are monitored for any adverse reactions. The hospital's Infusion Suite is equipped with comfortable settings to ensure a stress-free experience for patients. Most patients begin with an induction phase, receiving infusions at week 0, 2, and 6, followed by maintenance doses every 8 weeks thereafter.
Benefits of Infliximab for Crohn's Disease
Infliximab has been shown to be particularly effective in reducing symptoms of Crohn's Disease such as abdominal pain, diarrhea, and weight loss. It can also help achieve and maintain remission, potentially reducing the need for surgical interventions. Patients often experience improvement in their overall well-being and daily functioning. The ability to receive treatment locally at Addenbrooke's NHS Hospital means patients have access to leading care without the need to travel long distances.
Considerations and Side Effects
While infliximab is effective, it is important to consider potential side effects. These can include infusion reactions, increased risk of infections, and allergic responses. Prior to beginning treatment, patients will have a thorough evaluation at Addenbrooke's NHS Hospital to ensure its suitability. Continuous monitoring and regular follow-up appointments help manage any risks and ensure that patients receive the best possible care.
Frequently Asked Questions
What is Infliximab (Remicade) and how does it work for Crohn's Disease?
Infliximab, marketed as Remicade, is a biologic therapy that works by blocking a protein called tumor necrosis factor-alpha (TNF-alpha), reducing inflammation and suppressing the overactive immune response associated with Crohn's Disease.
How is Infliximab administered at Addenbrookes Hospital?
Infliximab is given as an intravenous infusion, meaning it is delivered directly into the bloodstream through a vein at Addenbrookes NHS Hospital under supervised medical conditions.
How long does an Infliximab infusion take?
An Infliximab infusion typically takes between 2 to 3 hours. Patients will be monitored during the infusion for any adverse reactions.
How often do I need to receive Infliximab infusions?
The initial treatment usually involves infusions at weeks 0, 2, and 6, followed by maintenance infusions every 8 weeks, although the schedule may vary based on individual patient needs.
What should I expect during my first Infliximab infusion?
During your first infusion, medical staff will check your vital signs and begin the intravenous administration of Infliximab. You'll be observed throughout to ensure you don't experience any adverse reactions.
What are the potential side effects of Infliximab?
Common side effects include infusion-related reactions such as headache, dizziness, rash, and fever. Serious side effects can occur as well, so it's important to report any unusual symptoms to your healthcare team.
Can I receive Infliximab if I have other medical conditions?
It's important to discuss your complete medical history with your doctor at Addenbrookes, as some conditions may affect the suitability of Infliximab or require additional precautions.
Will Infliximab interact with my other medications?
Tell your healthcare provider about all medications you are taking, as Infliximab may interact with other drugs. This includes over-the-counter drugs and supplements.
How should I prepare for my Infliximab infusion at Addenbrookes?
There are no special preparations needed, but it is advised to eat a light meal beforehand and wear comfortable clothing. Bring any medications you may need and plan for a way to get home safely.
Is Infliximab treatment covered by the NHS?
Yes, Infliximab is covered by the NHS for the treatment of Crohn's Disease when prescribed by a specialist at a hospital like Addenbrookes.
Can I continue working and doing daily activities while receiving Infliximab?
Many patients continue their normal activities while on Infliximab, although you should avoid heavy lifting or stressful activities on the day of the infusion. Discuss your specific circumstances with your healthcare provider.
What should I do if I experience side effects after the infusion?
Contact your healthcare provider immediately if you experience any adverse effects or symptoms after receiving an Infliximab infusion, especially if they are severe or persistent.
How will I know if Infliximab is working for my Crohn's Disease?
Improvement in symptoms can be seen as early as a few weeks after starting treatment. Regular follow-ups and assessments will help determine the effectiveness of the therapy for your condition.
Can I receive Infliximab infusions if I'm pregnant or planning to become pregnant?
Discuss your plans and any concerns about pregnancy with your healthcare provider, as they will provide guidance based on your specific situation and latest clinical guidelines.
Who can I contact for more information about my Infliximab treatment at Addenbrookes?
For more information, you can contact your specialist team at Addenbrookes Hospital or the patient support services available through the NHS.
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- Videos shown by Youtube after a video has completed, have NOT been reviewed by ERGSY.
- To view, click the arrow in centre of video.
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- You may need to turn these on, and choose your preferred language.
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