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Neurosurgery for Epilepsy

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Neurosurgery for Epilepsy: Understanding the Options and Outcomes

Introduction to Epilepsy

Epilepsy is a neurological disorder characterized by recurring seizures. These seizures result from abnormal electrical activity in the brain and can vary widely in severity. In the United Kingdom, approximately 600,000 people are affected by epilepsy. While medication remains the primary treatment, about 30% of patients do not achieve adequate seizure control through drug therapy alone. For these individuals, neurosurgery can be a viable option.

Types of Neurosurgical Procedures

Several neurosurgical approaches are available for treating epilepsy: 1. **Resective Surgery**: This involves removing the portion of the brain where seizures originate. The most common type is temporal lobectomy, which has a high success rate in reducing or eliminating seizures. 2. **Lesionectomy**: When seizures are caused by specific abnormalities in the brain, such as a tumour or malformation, surgeons can remove these lesions to control the seizures. 3. **Corpus Callosotomy**: This procedure entails severing the nerve fibres that connect the brain's two hemispheres to prevent the spread of seizures from one side of the brain to the other. 4. **Multiple Subpial Transection (MST)**: Used when the seizure focus is near vital brain areas that control movement or language, MST involves making cuts in the brain's grey matter to interrupt seizure pathways without removing tissue.

Pre-surgical Evaluation

Before surgery, patients undergo an extensive pre-surgical evaluation to pinpoint the seizure focus and ensure they are good candidates for surgery. This evaluation often includes: - **Prolonged Video-EEG Monitoring**: To record seizures and identify their origin. - **MRI and PET Scans**: To detect structural abnormalities in the brain. - **Neuropsychological Testing**: To assess cognitive function and predict potential impacts of surgery.

Benefits and Risks

Neurosurgery for epilepsy can offer significant benefits, including reduced seizure frequency, improved quality of life, and enhanced cognitive and social functioning. However, it also carries risks such as infection, bleeding, and neurological deficits.

Post-surgery Recovery and Outcome

Recovery from neurosurgery can vary. Most patients require a hospital stay of several days followed by a period of rehabilitation. Success rates are encouraging – up to 70% of patients undergoing resective surgery become seizure-free, while another 20% experience a notable reduction in seizure frequency.

Conclusion

For individuals in the UK with drug-resistant epilepsy, neurosurgery offers a promising path toward better seizure control and improved quality of life. It is essential to work closely with a specialised epilepsy care team to ensure a thorough evaluation and to weigh the potential benefits against the risks.

Frequently Asked Questions

What is epilepsy surgery?

Epilepsy surgery is a neurosurgical procedure aimed at removing or altering the area of the brain where seizures originate to reduce or eliminate seizures.

Who is a candidate for epilepsy surgery?

Candidates for epilepsy surgery are typically patients who have not responded to medication after trying multiple antiepileptic drugs and continue to experience debilitating seizures.

What types of epilepsy surgery are available?

Common types of epilepsy surgery include resective surgery, laser interstitial thermal therapy (LITT), disconnection procedures like corpus callosotomy, and neurostimulation techniques such as vagus nerve stimulation (VNS) and responsive neurostimulation (RNS).

How is the surgical area identified?

The surgical area is identified using advanced imaging techniques such as MRI, PET scans, and EEG monitoring, often combined with inpatient video EEG monitoring and neuropsychological testing.

What are the risks of epilepsy surgery?

Risks include infection, bleeding, neurological deficits, memory loss, and changes in cognition or behavior. Discussing specific risks with a neurosurgeon is crucial.

What is the success rate of epilepsy surgery?

Success rates vary depending on the type of surgery and the patient’s condition. Resective surgery can result in seizure freedom for approximately 60-80% of patients, while other procedures may reduce seizure frequency.

How long is the recovery time after epilepsy surgery?

Recovery time varies but generally involves a hospital stay of a few days to a week, followed by several weeks to months of gradual recovery and rehabilitation.

Will I need to stay on medication after epilepsy surgery?

Many patients continue to take antiepileptic drugs for months or even years after surgery. The goal is to eventually reduce or stop medications, but this is determined on an individual basis.

Are there any lifestyle changes necessary after epilepsy surgery?

Lifestyle changes may include modifications to activities during recovery, ongoing medication management, and regular follow-ups with healthcare providers to monitor seizure activity and overall health.

How do I prepare for epilepsy surgery?

Preparation involves a thorough evaluation by a multidisciplinary team, which may include imaging studies, neuropsychological testing, and sometimes an inpatient stay for video EEG monitoring.

Is epilepsy surgery covered by the NHS?

Yes, epilepsy surgery is generally covered by the NHS for eligible patients. However, eligibility needs to be established through comprehensive assessments performed by specialist teams.

What kind of follow-up care will I need after surgery?

Follow-up care involves regular appointments with your neurosurgeon and neurologist, medication adjustments, and possibly additional therapies such as occupational or speech therapy, depending on your recovery.

Can children undergo epilepsy surgery?

Yes, children can undergo epilepsy surgery, especially if their seizures are significantly affecting their quality of life and are not controlled by medication. Assessments and procedures are tailored specifically for the paediatric population.

What are the psychological effects of epilepsy surgery?

Psychological effects can vary: some patients experience improvements in mood and quality of life, while others may face challenges such as anxiety or depression. Psychological support and counselling are important aspects of the recovery process.

Can epilepsy return after surgery?

While epilepsy surgery can significantly reduce or eliminate seizures, there is a possibility that seizures may return. Continuous monitoring and follow-up care are essential for managing any potential recurrence.

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